Some Major Questions in Cardiovascular Tissue Engineering

Soft tissuesWhat is the best way to establish a blood supply to a tissue-engineered construct, such as a cardiac patch?
CellsHow do very few hESC–CMs surviving in the heart affect ventricular arrhythmia?
Are patient-specific (autologous) approaches best, or can we address issues with allogenic donors?
ImagingWhat approaches and methods are best to assess viability and function of an engineered tissue in vivo?
  • hESC–CM indicates human embryonic stem cells–cardiomyocytes.