On the cover: Photomicrograph showing an adult rat pulmonary artery vascular smooth muscle cell cultured on denatured type I collagen following (immuno) fluorescent staining for tenascin-C (green), F-actin (red) and DNA (blue). Note that a physical continuum exists between tenascin-C and F-actin, indicating that cytoskeletal contraction (vasoconstriction) and extracellular matrix remodeling are intimately linked. See related article, page 837.