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About This Cover
Volume 99, Issue 3; August 4, 2006
Editorials
Molecular Medicine
Cellular Biology
Integrative Physiology
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Editorials
Life, Sudden Death, and Intracellular Calcium
D.A. Eisner, L.A. Venetucci, and A.W. Trafford
Circ Res. 2006;99:223-224, doi:10.1161/01.RES.0000236790.08267.74
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Myosin Light Chain 2 Into the Mainstream of Cardiac Development and Contractility
Richard L. Moss and Daniel P. Fitzsimons
Circ Res. 2006;99:225-227, doi:10.1161/01.RES.0000236793.88131.dc
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Containing Hypertrophy With a PICOT Fence
Gerald W. Dorn, II
Circ Res. 2006;99:228-230, doi:10.1161/01.RES.0000236795.57759.45
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Small Molecule Approaches for Promoting Ischemic Tissue Vascularization
Federico Bussolino
Circ Res. 2006;99:231-233, doi:10.1161/01.RES.0000236801.85717.7e
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Does 2-Methoxyestradiol Represent the New and Improved Hormone Replacement Therapy for Atherosclerosis?
Ana Paula V. Dantas and Kathryn Sandberg
Circ Res. 2006;99:234-237, doi:10.1161/01.RES.0000236802.00855.cd
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Rho-Kinase: A Potential Link Between Hypercholesterolemia and Abnormal Vascular Smooth Muscle Contraction
James K. Liao
Circ Res. 2006;99:238-239, doi:10.1161/01.RES.0000236798.01988.5d
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Molecular Medicine
Hypoxia Regulates Bone Morphogenetic Protein Signaling Through C-TerminalBinding Protein 1
Xinqi Wu, Mun Seog Chang, S. Alex Mitsialis, and Stella Kourembanas
Circ Res. 2006;99:240-247; published online before print July 13 2006, doi:10.1161/01.RES.0000237021.65103.24
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Endoglin Regulates Cyclooxygenase-2 Expression and Activity
Mirjana Jerkic, Juan V. Rivas-Elena, Juan F. Santibanez, Marta Prieto, Alicia Rodríguez-Barbero, Fernando Perez-Barriocanal, Miguel Pericacho, Miguel Arévalo, Calvin P.H. Vary, Michelle Letarte, Carmelo Bernabeu, and Jose M. López-Novoa
Circ Res. 2006;99:248-256; published online before print July 13 2006, doi:10.1161/01.RES.0000236755.98627.69
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Identification of Sokotrasterol Sulfate As a Novel Proangiogenic Steroid
Siun Murphy, Bruno Larrivée, Ingrid Pollet, Kyle S. Craig, David E. Williams, Xin-Hui Huang, Megan Abbott, Fred Wong, Cameron Curtis, Thomas P. Conrads, Timothy Veenstra, Mira Puri, York Hsiang, Michel Roberge, Raymond J. Andersen, and Aly Karsan
Circ Res. 2006;99:257-265; published online before print June 22 2006, doi:10.1161/01.RES.0000233316.17882.33
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2-Methoxyestradiol, an Estradiol Metabolite, Inhibits Neointima Formation and Smooth Muscle Cell Growth via Double Blockade of the Cell Cycle
Federica Barchiesi, Edwin K. Jackson, Juergen Fingerle, Delbert G. Gillespie, Bernhard Odermatt, and Raghvendra K. Dubey
Circ Res. 2006;99:266-274; published online before print June 22 2006, doi:10.1161/01.RES.0000233318.85181.2e
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Cellular Biology
Activation of the Unfolded Protein Response in Infarcted Mouse Heart and Hypoxic Cultured Cardiac Myocytes
Donna J. Thuerauf, Marie Marcinko, Natalie Gude, Marta Rubio, Mark A. Sussman, and Christopher C. Glembotski
Circ Res. 2006;99:275-282; published online before print June 22 2006, doi:10.1161/01.RES.0000233317.70421.03
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Sarcoplasmic Reticulum and Nuclear Envelope Are One Highly Interconnected Ca
2+
Store Throughout Cardiac Myocyte
Xu Wu and Donald M. Bers
Circ Res. 2006;99:283-291; published online before print June 22 2006, doi:10.1161/01.RES.0000233386.02708.72
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Arrhythmogenesis in Catecholaminergic Polymorphic Ventricular Tachycardia: Insights From a RyR2 R4496C Knock-In Mouse Model
Nian Liu, Barbara Colombi, Mirella Memmi, Spyros Zissimopoulos, Nicoletta Rizzi, Sara Negri, Marcello Imbriani, Carlo Napolitano, F. Anthony Lai, and Silvia G. Priori
Circ Res. 2006;99:292-298; published online before print July 6 2006, doi:10.1161/01.RES.0000235869.50747.e1
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Cholesterol Primes Vascular Smooth Muscle to Induce Ca
2
Sensitization Mediated by a SphingosylphosphorylcholineRho-Kinase Pathway: Possible Role for Membrane Raft
Noriyasu Morikage, Hiroko Kishi, Masafumi Sato, Fengling Guo, Satoshi Shirao, Takashi Yano, Masaaki Soma, Kimikazu Hamano, Kensuke Esato, and Sei Kobayashi
Circ Res. 2006;99:299-306; published online before print July 6 2006, doi:10.1161/01.RES.0000235877.33682.e9
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Integrative Physiology
PICOT Inhibits Cardiac Hypertrophy and Enhances Ventricular Function and Cardiomyocyte Contractility
Dongtak Jeong, Hyeseon Cha, Eunyoung Kim, Misuk Kang, Dong Kwon Yang, Ji Myoung Kim, Pyoung Oh Yoon, Jae Gyun Oh, Oliver Y. Bernecker, Susumu Sakata, Le Thi Thu, Lei Cui, Young-Hoon Lee, Do Han Kim, Sun-Hee Woo, Ronglih Liao, Roger J. Hajjar, and Woo Jin Park
Circ Res. 2006;99:307-314; published online before print June 29 2006, doi:10.1161/01.RES.0000234780.06115.2c
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Essential Role of ICAM-1/CD18 in Mediating EPC Recruitment, Angiogenesis, and Repair to the Infarcted Myocardium
Yaojiong Wu, James E. Ip, Jing Huang, Lunan Zhang, Kenichi Matsushita, Choong-Chin Liew, Richard E. Pratt, and Victor J. Dzau
Circ Res. 2006;99:315-322; published online before print July 6 2006, doi:10.1161/01.RES.0000235986.35957.a3
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Cardiac Myosin Light Chain-2: A Novel Essential Component of Thick-Myofilament Assembly and Contractility of the Heart
Wolfgang Rottbauer, Georgia Wessels, Tillman Dahme, Steffen Just, Nicole Trano, David Hassel, Charles Geoffrey Burns, Hugo A. Katus, and Mark C. Fishman
Circ Res. 2006;99:323-331; published online before print June 29 2006, doi:10.1161/01.RES.0000234807.16034.fe
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