On the cover: Photomicrograph of a cross section of adult human epicardial coronary artery, showing a confocal image of fluorescent dual-labeling immunocytochemistry, where primary antisera to natriuretic peptide receptor-A (NPR-A) staining to smooth muscle cells has been visualised using green fluorescence and the endothelium lining the lumen vessel localized in red fluorescence with primary antisera to vWF. A novel radio-iodinated analog of the natriuretic peptide DNP, originally identified from the venom of the Green Mamba snake (Dendroaspis angusticeps), was synthesised to characterize NPR-A receptors in the human cardiovascular system. Image of a green mamba is acknowledged as copyright of The Zoological Society of London. See related article, page 183.