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About This Cover
Volume 99, Issue 12; December 8, 2006
Editorials
Reviews
Molecular Medicine
Cellular Biology
Integrative Physiology
Clinical Research
UltraRapid Communications
Index
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Editorials
Tuning the Beat: Differential Expression of Ion Channels in the Sinus Node
Stefan Kääb
Circ Res. 2006;99:1283-1284, doi:10.1161/01.RES.0000253088.77311.b1.
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On the Pathophysiological Implications of an Intracellular Renin Receptor
Walmor C. De Mello
Circ Res. 2006;99:1285-1286, doi:10.1161/01.RES.0000253141.65450.fc.
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ß-Catenin Nuclear Activation: Common Pathway Between Wnt and Growth Factor Signaling in Vascular Smooth Muscle Cell Proliferation?
Thierry Couffinhal, Pascale Dufourcq, and Cécile Duplàa
Circ Res. 2006;99:1287-1289, doi:10.1161/01.RES.0000253139.82251.31.
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Phospholemman and the Cardiac Sodium Pump: Protein Kinase C, Take a Bow
William Fuller and Michael J. Shattock
Circ Res. 2006;99:1290-1292, doi:10.1161/01.RES.0000253090.54488.81.
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Reviews
Activation of Platelet Function Through G ProteinCoupled Receptors
Stefan Offermanns
Circ Res. 2006;99:1293-1304, doi:10.1161/01.RES.0000251742.71301.16.
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Regulation of G Protein and Mitogen-Activated Protein Kinase Signaling by Ubiquitination: Insights From Model Organisms
Yuqi Wang and Henrik G. Dohlman
Circ Res. 2006;99:1305-1314, doi:10.1161/01.RES.0000251641.57410.81.
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Heart Failure and Protein Quality Control
Xuejun Wang and Jeffrey Robbins
Circ Res. 2006;99:1315-1328, doi:10.1161/01.RES.0000252342.61447.a2.
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Molecular Medicine
Regulation of Smooth Muscle Cell Proliferation by ß-Catenin/T-Cell Factor Signaling Involves Modulation of Cyclin D1 and p21 Expression
Helen Quasnichka, Sadie C. Slater, Cressida A. Beeching, Manfred Boehm, Graciela B. Sala-Newby, and Sarah J. George
Circ Res. 2006;99:1329-1337; published online before print November 22 2006, doi:10.1161/01.RES.0000253533.65446.33.
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Data Supplement
Wilms Tumor 1Associating Protein Regulates the Proliferation of Vascular Smooth Muscle Cells
Theodore W. Small, Zuzana Bolender, Clara Bueno, Caroline ONeil, Zengxuan Nong, Walter Rushlow, Nagalingham Rajakumar, Christopher Kandel, Jennifer Strong, Joaquin Madrenas, and J. Geoffrey Pickering
Circ Res. 2006;99:1338-1346; published online before print November 9 2006, doi:10.1161/01.RES.0000252289.79841.d3.
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Transcriptional Silencing of the Death Gene BNIP3 by Cooperative Action of NF-
B and Histone Deacetylase 1 in Ventricular Myocytes
James Shaw, Tong Zhang, Marek Rzeszutek, Natalia Yurkova, Delphine Baetz, James R. Davie, and Lorrie A. Kirshenbaum
Circ Res. 2006;99:1347-1354; published online before print November 2 2006, doi:10.1161/01.RES.0000251744.06138.50.
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A Novel Signal Transduction Cascade Involving Direct Physical Interaction of the Renin/Prorenin Receptor With the Transcription Factor Promyelocytic Zinc Finger Protein
Jan H. Schefe, Mario Menk, Jana Reinemund, Karin Effertz, Robin M. Hobbs, Pier Paolo Pandolfi, Patricia Ruiz, Thomas Unger, and Heiko Funke-Kaiser
Circ Res. 2006;99:1355-1366; published online before print November 2 2006, doi:10.1161/01.RES.0000251700.00994.0d.
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Cellular Biology
1
-Adrenergic Receptors Activate AKT via a Pyk2/PDK-1 Pathway That Is Tonically Inhibited by Novel Protein Kinase C Isoforms in Cardiomyocytes
Jianfen Guo, Abdelkarim Sabri, Hasnae Elouardighi, Vitalyi Rybin, and Susan F. Steinberg
Circ Res. 2006;99:1367-1375; published online before print November 16 2006, doi:10.1161/01.RES.0000252830.01581.fd.
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Phospholemman Phosphorylation Mediates the Protein Kinase CDependent Effects on Na
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/K
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Pump Function in Cardiac Myocytes
Fei Han, Julie Bossuyt, Sanda Despa, Amy L. Tucker, and Donald M. Bers
Circ Res. 2006;99:1376-1383; published online before print November 9 2006, doi:10.1161/01.RES.0000251667.73461.fb.
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Integrative Physiology
Differential Expression of Ion Channel Transcripts in Atrial Muscle and Sinoatrial Node in Rabbit
James O. Tellez, Halina Dobrzynski, Ian D. Greener, Gillian M. Graham, Emma Laing, Haruo Honjo, Simon J. Hubbard, Mark R. Boyett, and Rudi Billeter
Circ Res. 2006;99:1384-1393; published online before print November 2 2006, doi:10.1161/01.RES.0000251717.98379.69.
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Induction of Heat Shock Response Protects the Heart Against Atrial Fibrillation
Bianca J. J. M. Brundel, Akiko Shiroshita-Takeshita, XiaoYan Qi, Yung-Hsin Yeh, Denis Chartier, Isabelle C. van Gelder, Robert H. Henning, Harm H. Kampinga, and Stanley Nattel
Circ Res. 2006;99:1394-1402; published online before print November 16 2006, doi:10.1161/01.RES.0000252323.83137.fe.
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Integrin Activation in the Heart: A Link Between Electrical and Contractile Dysfunction?
Maria L. Valencik, Dongfang Zhang, Bonnie Punske, Ping Hu, John A. McDonald, and Sheldon E. Litwin
Circ Res. 2006;99:1403-1410; published online before print November 9 2006, doi:10.1161/01.RES.0000252291.88540.ac.
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Upregulation of Heat Shock Transcription Factor 1 Plays a Critical Role in Adaptive Cardiac Hypertrophy
Masaya Sakamoto, Tohru Minamino, Haruhiro Toko, Yosuke Kayama, Yunzeng Zou, Masanori Sano, Eiichi Takaki, Teruhiko Aoyagi, Katsuyoshi Tojo, Naoko Tajima, Akira Nakai, Hiroyuki Aburatani, and Issei Komuro
Circ Res. 2006;99:1411-1418; published online before print November 9 2006, doi:10.1161/01.RES.0000252345.80198.97.
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Clinical Research
Haptoglobin Genotype Is a Regulator of Reverse Cholesterol Transport in Diabetes In Vitro and In Vivo
Rabea Asleh, Rachael Miller-Lotan, Michael Aviram, Tony Hayek, Michael Yulish, Joanne E. Levy, Benjamin Miller, Shany Blum, Uzi Milman, Chen Shapira, and Andrew P. Levy
Circ Res. 2006;99:1419-1425; published online before print November 2 2006, doi:10.1161/01.RES.0000251741.65179.56.
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Rho Kinase Inhibition Improves Endothelial Function in Human Subjects With Coronary Artery Disease
Anju Nohria, Matthew E. Grunert, Yoshiyuki Rikitake, Kensuke Noma, Adnan Prsic, Peter Ganz, James K. Liao, and Mark A. Creager
Circ Res. 2006;99:1426-1432; published online before print November 9 2006, doi:10.1161/01.RES.0000251668.39526.c7.
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UltraRapid Communications
A Nuclear Receptor CorepressorDependent Pathway Mediates Suppression of Cytokine-Induced C-Reactive Protein Gene Expression by Liver X Receptor
Florian Blaschke, Yasunori Takata, Evren Caglayan, Alan Collins, Peter Tontonoz, Willa A. Hsueh, and Rajendra K. Tangirala
Circ Res. 2006;99:e88-e99; published online before print November 16 2006, doi:10.1161/01.RES.0000252878.34269.06.
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Index
Author Index
Circ Res. 2006;99:1434-1438.
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