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About This Cover
Volume 104, Issue 1; January 2, 2009
Editorials
Reports
Reviews
Molecular Medicine
Cellular Biology
Integrative Physiology
UltraRapid Communications
Letters to the Editor
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Editorials
Serotonin 5-HT
2B
Receptor in Cardiac Fibroblast Contributes to Cardiac Hypertrophy: A New Therapeutic Target for Heart Failure?
Kou-Gi Shyu
Circ Res. 2009;104:1-3, doi:10.1161/CIRCRESAHA.108.191122
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Suppression of Peroxisome Proliferator-Activated Receptor-
Activity by Angiotensin II in Vascular Smooth Muscle Involves Bcr Kinase: The Fire That Drowns The Water
Ernesto L. Schiffrin and Pierre Paradis
Circ Res. 2009;104:4-6, doi:10.1161/CIRCRESAHA.108.191155
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O
-Linked β-
N
-Acetylglucosamine: A New Piece of the Cardioprotection Puzzle?
James M. Downey and Michael V. Cohen
Circ Res. 2009;104:7-8, doi:10.1161/CIRCRESAHA.108.191163
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A New Look at the Eye: Aldosterone and Mineralocorticoid Receptors As Novel Targets in Retinal Vasculopathy
Rhian M. Touyz and Glaucia E. Callera
Circ Res. 2009;104:9-11, doi:10.1161/CIRCRESAHA.108.191288
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Transcriptional and Posttranslational Modifications of Titin: Implications for Diastole
Attila Borbély, Loek van Heerebeek, and Walter J. Paulus
Circ Res. 2009;104:12-14, doi:10.1161/CIRCRESAHA.108.191130
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Reports
Ischemic Postconditioning in Pigs: No Causal Role for RISK Activation
Andreas Skyschally, Patrick van Caster, Kerstin Boengler, Petra Gres, Judith Musiolik, Dustin Schilawa, Rainer Schulz, and Gerd Heusch
Circ Res. 2009;104:15-18; published online before print November 26 2008, doi:10.1161/CIRCRESAHA.108.186429
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Data Supplement
Reviews
Developmental Basis for Electrophysiological Heterogeneity in the Ventricular and Outflow Tract Myocardium As a Substrate for Life-Threatening Ventricular Arrhythmias
Bastiaan J.D. Boukens, Vincent M. Christoffels, Ruben Coronel, and Antoon F.M. Moorman
Circ Res. 2009;104:19-31, doi:10.1161/CIRCRESAHA.108.188698
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Molecular Medicine
Proteomics Identifies Thymidine Phosphorylase As a Key Regulator of the Angiogenic Potential of Colony-Forming Units and Endothelial Progenitor Cell Cultures
Giordano Pula, Ursula Mayr, Colin Evans, Marianna Prokopi, Dina S. Vara, Xiaoke Yin, Zoe Astroulakis, Qingzhong Xiao, Jonathan Hill, Qingbo Xu, and Manuel Mayr
Circ Res. 2009;104:32-40; published online before print November 20 2008, doi:10.1161/CIRCRESAHA.108.182261
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Unique Hexosaminidase Reduces Metabolic Survival Signal and Sensitizes Cardiac Myocytes to Hypoxia/Reoxygenation Injury
Gladys A. Ngoh, Heberty T. Facundo, Tariq Hamid, Wolfgang Dillmann, Natasha E. Zachara, and Steven P. Jones
Circ Res. 2009;104:41-49; published online before print November 20 2008, doi:10.1161/CIRCRESAHA.108.189431
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An Ezrin/Calpain/PI3K/AMPK/eNOS
s1179
Signaling Cascade Mediating VEGF-Dependent Endothelial Nitric Oxide Production
Ji-Youn Youn, Ting Wang, and Hua Cai
Circ Res. 2009;104:50-59; published online before print November 26 2008, doi:10.1161/CIRCRESAHA.108.178467
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Inflammatory Interaction Between LIGHT and Proteinase-Activated Receptor-2 in Endothelial Cells: Potential Role in Atherogenesis
Wiggo J. Sandberg, Bente Halvorsen, Arne Yndestad, Camilla Smith, Kari Otterdal, Frank R. Brosstad, Stig S. Frøland, Peder S. Olofsson, Jan K. Damås, Lars Gullestad, Göran K. Hansson, Erik Øie, and Pål Aukrust
Circ Res. 2009;104:60-68; published online before print November 20 2008, doi:10.1161/CIRCRESAHA.108.188078
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Bcr Kinase Activation by Angiotensin II Inhibits Peroxisome Proliferator-Activated Receptor
Transcriptional Activity in Vascular Smooth Muscle Cells
Jeffrey D. Alexis, Nadan Wang, Wenyi Che, Nicole Lerner-Marmarosh, Abha Sahni, Vyacheslav A. Korshunov, Yiping Zou, Bo Ding, Chen Yan, Bradford C. Berk, and Jun-ichi Abe
Circ Res. 2009;104:69-78; published online before print November 20 2008, doi:10.1161/CIRCRESAHA.108.188409
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Cellular Biology
Oxidative Stress–Induced Afterdepolarizations and Calmodulin Kinase II Signaling
Lai-Hua Xie, Fuhua Chen, Hrayr S. Karagueuzian, and James N. Weiss
Circ Res. 2009;104:79-86; published online before print November 26 2008, doi:10.1161/CIRCRESAHA.108.183475
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Protein Kinase G Modulates Human Myocardial Passive Stiffness by Phosphorylation of the Titin Springs
Martina Krüger, Sebastian Kötter, Anika Grützner, Patrick Lang, Christian Andresen, Margaret M. Redfield, Elke Butt, Cris G. dos Remedios, and Wolfgang A. Linke
Circ Res. 2009;104:87-94; published online before print November 20 2008, doi:10.1161/CIRCRESAHA.108.184408
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Ca
2+
-Independent Alterations in Diastolic Sarcomere Length and Relaxation Kinetics in a Mouse Model of Lipotoxic Diabetic Cardiomyopathy
Thomas P. Flagg, Olivier Cazorla, Maria S. Remedi, Todd E. Haim, Michael A. Tones, Anthony Bahinski, Randal E. Numann, Attila Kovacs, Jean E. Schaffer, Colin G. Nichols, and Jeanne M. Nerbonne
Circ Res. 2009;104:95-103; published online before print November 20 2008, doi:10.1161/CIRCRESAHA.108.186809
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Mitochondrial Regulation of Sarcoplasmic Reticulum Ca
2+
Content in Vascular Smooth Muscle Cells
Damon Poburko, Chiu-Hsiang Liao, Cornelis van Breemen, and Nicolas Demaurex
Circ Res. 2009;104:104-112; published online before print November 20 2008, doi:10.1161/CIRCRESAHA.108.180612
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Integrative Physiology
Serotonin and Angiotensin Receptors in Cardiac Fibroblasts Coregulate Adrenergic-Dependent Cardiac Hypertrophy
Fabrice Jaffré, Philippe Bonnin, Jacques Callebert, Haythem Debbabi, Vincent Setola, Stéphane Doly, Laurent Monassier, Bertrand Mettauer, Burns C. Blaxall, Jean-Marie Launay, and Luc Maroteaux
Circ Res. 2009;104:113-123; published online before print November 20 2008, doi:10.1161/CIRCRESAHA.108.180976
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Identification of a Retinal Aldosterone System and the Protective Effects of Mineralocorticoid Receptor Antagonism on Retinal Vascular Pathology
Jennifer L. Wilkinson-Berka, Genevieve Tan, Kassie Jaworski, and Antonia G. Miller
Circ Res. 2009;104:124-133; published online before print November 26 2008, doi:10.1161/CIRCRESAHA.108.176008
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UltraRapid Communications
Genetic Manipulation of Periostin Expression in the Heart Does Not Affect Myocyte Content, Cell Cycle Activity, or Cardiac Repair
Angela Lorts, Jennifer A. Schwanekamp, John W. Elrod, Michelle A. Sargent, and Jeffery D. Molkentin
Circ Res. 2009;104:e1-e7; published online before print November 26 2008, doi:10.1161/CIRCRESAHA.108.188649
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Letters to the Editor
Response to the Letter by Rose et al
Daniël A. Pijnappels, Martin J. Schalij, and Douwe E. Atsma
Circ Res. 2009;104:e8, doi:10.1161/CIRCRESAHA.108.190132
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