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About This Cover
Volume 102, Issue 8; April 25, 2008
Editorials
Reviews
Molecular Medicine
Cellular Biology
Integrative Physiology
Clinical Research
UltraRapid Communications
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Editorials
Chlamydophila pneumoniae
and Endothelial Activation: The Smoke That Precedes the Fire of Atherosclerosis?
Sean P. Didion
Circ Res. 2008;102:861-863, doi:10.1161/CIRCRESAHA.108.175547
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Living on the Edge: Hypoxia-Induced Tissue Damage
Evren Caglayan and Stephan Rosenkranz
Circ Res. 2008;102:864-865, doi:10.1161/CIRCRESAHA.108.175562
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Arginine and Arginase: Endothelial NO Synthase Double Crossed?
Paul M. Vanhoutte
Circ Res. 2008;102:866-868, doi:10.1161/CIRCRESAHA.108.175570
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Hyperhomocysteinemia and Occlusive Vascular Disease: An Emergent Role for Fibroblast Growth Factor 2
Miguel Ángel Medina
Circ Res. 2008;102:869-870, doi:10.1161/CIRCRESAHA.108.175588
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PI3K
Helps an SDF Seeking Home ... for EPCs
Ziad Mallat
Circ Res. 2008;102:871-872, doi:10.1161/CIRCRESAHA.108.175638
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Reviews
Epigenetic Regulation of Vascular Endothelial Gene Expression
Charles C. Matouk and Philip A. Marsden
Circ Res. 2008;102:873-887, doi:10.1161/CIRCRESAHA.107.171025
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Molecular Medicine
Simvastatin Reduces
Chlamydophila pneumoniae
–Mediated Histone Modifications and Gene Expression in Cultured Human Endothelial Cells
Bernd Schmeck, Wiebke Beermann, Philippe Dje NGuessan, Andreas C. Hocke, Bastian Opitz, Julia Eitel, Quoc Thai Dinh, Martin Witzenrath, Matthias Krüll, Norbert Suttorp, and Stefan Hippenstiel
Circ Res. 2008;102:888-895; published online before print February 28 2008, doi:10.1161/CIRCRESAHA.107.161307
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Data Supplement
X-Linked Inhibitor of Apoptosis Protein Is an Important Regulator of Vascular Endothelial Growth Factor–Dependent Bovine Aortic Endothelial Cell Survival
Jongmin Kim, Jongbong Park, Seungmin Choi, Sung-Gil Chi, Amy L. Mowbray, Hanjoong Jo, and Heonyong Park
Circ Res. 2008;102:896-904; published online before print February 28 2008, doi:10.1161/CIRCRESAHA.107.163667
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Oxygen Deprivation Triggers Upregulation of Early Growth Response-1 by the Receptor for Advanced Glycation End Products
Jong Sun Chang, Thoralf Wendt, Wu Qu, Linghua Kong, Yu Shan Zou, Ann Marie Schmidt, and Shi-Fang Yan
Circ Res. 2008;102:905-913; published online before print March 6 2008, doi:10.1161/CIRCRESAHA.107.165308
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Bone Morphogenetic Protein-9 Is a Circulating Vascular Quiescence Factor
Laurent David, Christine Mallet, Michelle Keramidas, Noël Lamandé, Jean-Marie Gasc, Sophie Dupuis-Girod, Henri Plauchu, Jean-Jacques Feige, and Sabine Bailly
Circ Res. 2008;102:914-922; published online before print February 28 2008, doi:10.1161/CIRCRESAHA.107.165530
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Endothelial Arginase II: A Novel Target for the Treatment of Atherosclerosis
Sungwoo Ryoo, Gaurav Gupta, Alexandre Benjo, Hyun Kyo Lim, Andre Camara, Gautam Sikka, Hyun Kyung Lim, Jayson Sohi, Lakshmi Santhanam, Kevin Soucy, Eric Tuday, Ezra Baraban, Monica Ilies, Gary Gerstenblith, Daniel Nyhan, Artin Shoukas, David W. Christianson, Nicholas J. Alp, Hunter C. Champion, David Huso, and Dan E. Berkowitz
Circ Res. 2008;102:923-932; published online before print February 28 2008, doi:10.1161/CIRCRESAHA.107.169573
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Homocysteine Inhibits Arterial Endothelial Cell Growth Through Transcriptional Downregulation of Fibroblast Growth Factor-2 Involving G Protein and DNA Methylation
Po-Yuan Chang, Shao-Chun Lu, Chii-Ming Lee, Yi-Jie Chen, Tracey A. Dugan, Wen-Huei Huang, Shwu-Fen Chang, Warren S.L. Liao, Chu-Huang Chen, and Yuan-Teh Lee
Circ Res. 2008;102:933-941; published online before print February 28 2008, doi:10.1161/CIRCRESAHA.108.171082
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Cellular Biology
Phosphatidylinositol-3-Kinase-
Is Integral to Homing Functions of Progenitor Cells
Emmanouil Chavakis, Guillaume Carmona, Carmen Urbich, Stephan Göttig, Reinhard Henschler, Josef M. Penninger, Andreas M. Zeiher, Triantafyllos Chavakis, and Stefanie Dimmeler
Circ Res. 2008;102:942-949; published online before print March 6 2008, doi:10.1161/CIRCRESAHA.107.164376
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Sphingosine-1-Phosphate Induces an Antiinflammatory Phenotype in Macrophages
Jeniter E. Hughes, Suseela Srinivasan, Kevin R. Lynch, Richard L. Proia, Pawel Ferdek, and Catherine C. Hedrick
Circ Res. 2008;102:950-958; published online before print March 6 2008, doi:10.1161/CIRCRESAHA.107.170779
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Integrative Physiology
Epac Mediates β-Adrenergic Receptor–Induced Cardiomyocyte Hypertrophy
Mélanie Métrich, Alexandre Lucas, Monique Gastineau, Jane-Lise Samuel, Christophe Heymes, Eric Morel, and Frank Lezoualch
Circ Res. 2008;102:959-965; published online before print March 6 2008, doi:10.1161/CIRCRESAHA.107.164947
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Negative-Feedback Loop Attenuates Hydrostatic Lung Edema via a cGMP-Dependent Regulation of Transient Receptor Potential Vanilloid 4
Jun Yin, Julia Hoffmann, Stephanie M. Kaestle, Nils Neye, Liming Wang, Joerg Baeurle, Wolfgang Liedtke, Songwei Wu, Hermann Kuppe, Axel R. Pries, and Wolfgang M. Kuebler
Circ Res. 2008;102:966-974; published online before print March 6 2008, doi:10.1161/CIRCRESAHA.107.168724
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Computer Three-Dimensional Reconstruction of the Atrioventricular Node
Jue Li, Ian D. Greener, Shin Inada, Vladimir P. Nikolski, Mitsuru Yamamoto, Jules C. Hancox, Henggui Zhang, Rudi Billeter, Igor R. Efimov, Halina Dobrzynski, and Mark R. Boyett
Circ Res. 2008;102:975-985; published online before print February 28 2008, doi:10.1161/CIRCRESAHA.108.172403
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Clinical Research
Acceleration of Cardiovascular Disease by a Dysfunctional Prostacyclin Receptor Mutation: Potential Implications for Cyclooxygenase-2 Inhibition
Eric Arehart, Jeremiah Stitham, Folkert W. Asselbergs, Karen Douville, Todd MacKenzie, Kristina M. Fetalvero, Scott Gleim, Zsolt Kasza, Yamini Rao, Laurie Martel, Sharon Segel, John Robb, Aaron Kaplan, Michael Simons, Richard J. Powell, Jason H. Moore, Eric B. Rimm, Kathleen A. Martin, and John Hwa
Circ Res. 2008;102:986-993; published online before print March 6 2008, doi:10.1161/CIRCRESAHA.107.165936
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UltraRapid Communications
Adrenergic Regulation of Cardiac Contractility Does Not Involve Phosphorylation of the Cardiac Ryanodine Receptor at Serine 2808
Scott M. MacDonnell, Gerardo García-Rivas, Joseph A. Scherman, Hajime Kubo, Xiongwen Chen, Héctor Valdivia, and Steven R. Houser
Circ Res. 2008;102:e65-e72; published online before print April 3 2008, doi:10.1161/CIRCRESAHA.108.174722
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Long-Term Doxycycline Is More Effective Than Atenolol to Prevent Thoracic Aortic Aneurysm in Marfan Syndrome Through the Inhibition of Matrix Metalloproteinase-2 and -9
Ada W.Y. Chung, H. H. Clarice Yang, Marek W. Radomski, and Cornelis van Breemen
Circ Res. 2008;102:e73-e85; published online before print April 3 2008, doi:10.1161/CIRCRESAHA.108.174367
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