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About This Cover
Volume 102, Issue 4; February 29, 2008
Editorials
Reviews
Molecular Medicine
Cellular Biology
Integrative Physiology
UltraRapid Communications
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Editorials
Annexin 2/Factor Xa–Mediated Signal Transduction
Salvatore V. Pizzo
Circ Res. 2008;102:389-391, doi:10.1161/CIRCRESAHA.108.172080.
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Disrupted Intercalated Discs: Is Kindlin-2 Required?
Cathy J. Hatcher and Craig T. Basson
Circ Res. 2008;102:392-394, doi:10.1161/CIRCRESAHA.108.172171.
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Discovery of an Intricate Balance: Gene Transcription, Cell Cycle, and Apoptosis
Jennifer L. Hall
Circ Res. 2008;102:395-397, doi:10.1161/CIRCRESAHA.108.172098.
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Vascular Endothelial Growth Factor Gene Regulation by HEXIM1 in Heart
Atsushi Asakura
Circ Res. 2008;102:398-400, doi:10.1161/CIRCRESAHA.108.172114.
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Reviews
Role of Mitochondrial Dysfunction in Insulin Resistance
Jeong-a Kim, Yongzhong Wei, and James R. Sowers
Circ Res. 2008;102:401-414, doi:10.1161/CIRCRESAHA.107.165472.
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Molecular Medicine
Mutation of the HEXIM1 Gene Results in Defects During Heart and Vascular Development Partly Through Downregulation of Vascular Endothelial Growth Factor
Monica M. Montano, Yong Qui Doughman, Huayun Deng, Laura Chaplin, Jianqi Yang, Nancy Wang, Qiang Zhou, Nicole L. Ward, and Michiko Watanabe
Circ Res. 2008;102:415-422; published online before print December 13 2007, doi:10.1161/CIRCRESAHA.107.157859.
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Data Supplement
Kindlin-2 Is an Essential Component of Intercalated Discs and Is Required for Vertebrate Cardiac Structure and Function
James J. Dowling, Elizabeth Gibbs, Mark Russell, Daniel Goldman, Jeremy Minarcik, Jeffrey A. Golden, and Eva L. Feldman
Circ Res. 2008;102:423-431; published online before print January 3 2008, doi:10.1161/CIRCRESAHA.107.161489.
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Dual Regulation of Cofilin Activity by LIM Kinase and Slingshot-1L Phosphatase Controls Platelet-Derived Growth Factor–Induced Migration of Human Aortic Smooth Muscle Cells
Alejandra San Martín, Moo Yeol Lee, Holly C. Williams, Kensaku Mizuno, Bernard Lassègue, and Kathy K. Griendling
Circ Res. 2008;102:432-438; published online before print December 20 2007, doi:10.1161/CIRCRESAHA.107.158923.
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Thyroid Hormone Regulates Developmental Titin Isoform Transitions via the Phosphatidylinositol-3-Kinase/ AKT Pathway
Martina Krüger, Christine Sachse, Wolfram H. Zimmermann, Thomas Eschenhagen, Stefanie Klede, and Wolfgang A. Linke
Circ Res. 2008;102:439-447; published online before print December 20 2007, doi:10.1161/CIRCRESAHA.107.162719.
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ADP Stimulates Human Endothelial Cell Migration via P2Y
1
Nucleotide Receptor–Mediated Mitogen-Activated Protein Kinase Pathways
Jianzhong Shen and Paul E. DiCorleto
Circ Res. 2008;102:448-456; published online before print January 3 2008, doi:10.1161/CIRCRESAHA.107.165795.
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Factor Xa Binding to Annexin 2 Mediates Signal Transduction via Protease-Activated Receptor 1
Gourab Bhattacharjee, Jasimuddin Ahamed, Rafal Pawlinski, Cheng Liu, Nigel Mackman, Wolfram Ruf, and Thomas S. Edgington
Circ Res. 2008;102:457-464; published online before print January 3 2008, doi:10.1161/CIRCRESAHA.107.167759.
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Cellular Biology
Functional Roles of a Ca
2+
-Activated K
+
Channel in Atrioventricular Nodes
Qian Zhang, Valeriy Timofeyev, Ling Lu, Ning Li, Anil Singapuri, Melissa K. Long, Chris T. Bond, John P. Adelman, and Nipavan Chiamvimonvat
Circ Res. 2008;102:465-471; published online before print December 20 2007, doi:10.1161/CIRCRESAHA.107.161778.
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The Cell Cycle Factor E2F-1 Activates Bnip3 and the Intrinsic Death Pathway in Ventricular Myocytes
Natalia Yurkova, James Shaw, Karen Blackie, Danielle Weidman, Ravi Jayas, Bryan Flynn, and Lorrie A. Kirshenbaum
Circ Res. 2008;102:472-479; published online before print December 20 2007, doi:10.1161/CIRCRESAHA.107.164731.
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The Scavenger Receptor Class B Type I Adaptor Protein PDZK1 Maintains Endothelial Monolayer Integrity
Weifei Zhu, Sonika Saddar, Divya Seetharam, Ken L. Chambliss, Christopher Longoria, David L. Silver, Ivan S. Yuhanna, Philip W. Shaul, and Chieko Mineo
Circ Res. 2008;102:480-487; published online before print January 3 2008, doi:10.1161/CIRCRESAHA.107.159079.
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Integrative Physiology
Molecular Mechanisms of Angiotensin II–Mediated Mitochondrial Dysfunction: Linking Mitochondrial Oxidative Damage and Vascular Endothelial Dysfunction
Abdulrahman K. Doughan, David G. Harrison, and Sergey I. Dikalov
Circ Res. 2008;102:488-496; published online before print December 20 2007, doi:10.1161/CIRCRESAHA.107.162800.
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Agonist-Stimulated Endothelial Nitric Oxide Synthase Activation and Vascular Relaxation: Role of eNOS Phosphorylation at Tyr83
David Fulton, Ling Ruan, Sarika G. Sood, Chunying Li, Qian Zhang, and Richard C. Venema
Circ Res. 2008;102:497-504; published online before print December 20 2007, doi:10.1161/CIRCRESAHA.107.162933.
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UltraRapid Communications
Angiotensin II–Inducible Platelet-Derived Growth Factor-D Transcription Requires Specific Ser/Thr Residues in the Second Zinc Finger Region of Sp1
Nicole Y. Tan, Valerie C. Midgley, Mary M. Kavurma, Fernando S. Santiago, Xiao Luo, Ryan Peden, Roger G. Fahmy, Michael C. Berndt, Mark P. Molloy, and Levon M. Khachigian
Circ Res. 2008;102:e38-e51; published online before print February 7 2008, doi:10.1161/CIRCRESAHA.107.167395.
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