Circulation Research Instructions for Authors
Circulation Research is an official journal of the American Heart Association and is the official journal of the Council on Basic Cardiovascular Sciences of the American Heart Association. Circulation Research is published as a print and online journal with 24 issues per year.
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Circulation Research is a forum for fundamental, mechanistic research of relevance to the cardiovascular system from various disciplines including biochemistry, biophysics, cellular biology, molecular biology, genetics, pathology, physiology, and pharmacology. The journal publishes manuscripts of the highest quality pertaining to basic cardiac and vascular biology and encourages the submission of work that uses state-of-the-art approaches to illuminate mechanisms of human disease. A special welcome is extended to translational research and to clinical research that yields fundamental insights; studies in humans or human tissues that advance our understanding of the basis of disease and the mechanism of therapies are an area of particular emphasis.
Criteria for Publication in Circulation Research
The mission of Circulation Research is to publish new information that constitutes an important conceptual advance vis-à-vis existing knowledge. Accordingly, the main criteria for acceptance are conceptual novelty, importance, and soundness of methodology. Priority is given to work that provides substantial new mechanistic insights into cardiovascular biology and disease. The editors also take into account whether a manuscript is of interest to the broad readership of Circulation Research. Even when the methodology is valid, significant novelty and impact are asine qua non for acceptance. Thus, studies that are well designed, well presented, methodologically sound, flawlessly executed, even mechanistically focused, but have low potential impact (e.g., they address a narrow field or have limited implications) and/or little conceptual novelty (e.g., they are variations or extensions of previous ideas, or merely incremental advances vs. previous work) are generally not published. Similarly, manuscripts that are otherwise outstanding but lack breadth of appeal (i.e., they are of interest to a very narrow segment of the readership) are usually not published.
All Original Research articles are published Online First on the same day of acceptance. After Online First publication, articles will be prepared for print and online publication, which includes copyediting, typesetting, proofreading, and author review. This process may lead to differences between the accepted version of the manuscript and the final, published version. Visit the Online First page for more information.
The editorial policy of Circulation Research is not to respond to pre-submission inquiries. The Editors of Circulation Research will not reply to emails from potential authors of Original Research inquiring if their manuscript or proposed manuscript topic is suitable for the journal. Authors should submit their manuscripts for formal peer review after following all of the guidelines listed in these Instructions to Authors.
The review process at Circulation Research is rapid. An editorial decision is usually made in fewer than 21 days for Regular Articles and in 7 days for Brief UltraRapid Communications. The editors encourage authors to provide the names of at least five potential reviewers who have not been collaborators or coauthors within the last three years and have not provided advice or critique of the submitted manuscript. Authors may list up to a maximum of three reviewers they wish to exclude.
For 2015, the average time from submission to first decision for all original research papers submitted to Circulation Research was 14 days.
Manuscripts submitted to Circulation Research are examined by the editors, who usually recruit three expert reviewers. Papers are carefully evaluated in terms of novelty, importance, methodology, and broad interest to the readership (vide infra). When appropriate, articles are also subjected to statistical review. Decisions are communicated by email. The editors will not discuss a decision regarding a manuscript over the phone. All rebuttals must be submitted in writing to the editorial office.
Address all correspondence to the Circulation Research Editorial Office:
Roberto Bolli, M.D.
Editor-in-Chief, Circulation Research
3355 Keswick Rd, Main Bldg 103
Baltimore, MD 21211
Online submission: http://circres-submit.aha-journals.org
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