In the article by Morimoto et al, “The Brain Renin-Angiotensin System in Transgenic Mice Carrying a Highly Regulated Human Renin Transgene” (Circ Res. 2002;90:80–86), the fourth paragraph of the Results section listed two incorrect callouts for panel designations in Figure 3. The corrected paragraph is provided below, and the corrected callouts appear in boldface.
“In PAC160 mice, anti-hREN immunoreactivity showed a fairly restricted distribution and was associated with both glia and neurons (Table). In the brain stem, anti-hREN immunoreactivity was found only in neurons in the dorsal cochlear nucleus, mostly in large diameter cells in its deeper layers but also in some cells in the granular layer (Figure 3A). Double-immunostaining with either NeuN or GFAP showed colocalization of hREN staining with NeuN staining (Figures 3A through 3D). Very little staining was seen elsewhere in the brain stem except the hypothalamus, where many hREN-immunostained processes, also immunoreactive for GFAP, were observed in the medial nuclear group (Figures 3K through 3N). In the forebrain, immunostained glial-like elements were seen in the cortex, particularly the piriform cortex and possibly in the hippocampus. In the hippocampus, however, small numbers of hREN immunoreactive neurons were consistently seen (Figures 3F through 3I). These were large diameter neurons located mostly in the strata oriens and radiatum and only rarely in the stratum pyramidale. All these cells were also NeuN-immunoreactive.”