Influence of Syrosingopine on the Cardiovascular Response to Acute Hypoxemia and Exercise
Large parenteral doses of a rauwolfia alkaloid, syrosiiigopine, administered to normal volunteers, although inducing a consistent reduction in pulse rate, did not interfere with the increase in cardiac output resulting from acute hypoxemia and exercise. The physiological and pharmacological implications of these observations are discussed.
- Received April 19, 1961.
- © 1961 American Heart Association, Inc.