Angiotensin, the Renal Pressor Hormone
We have shown the side groups of angiotensin that are necessary for biological activity. Additional evidence is given that angiotensin decapeptide has little or no biological activity and exerts its effect only through the octapeptide. Even though none of the analogues of angiotensin have inhibitory action on the parent compound, the information obtained from studying these compounds could lead to the synthesis of inhibitors.
- © 1961 American Heart Association, Inc.