Effect of Insulin in the Induction and Regression of Atherosclerosis in the Chick
Insulin administration to intact cockerels made atherosclerotic by the feeding of a cholesterol-oil-containing diet prevented regression of coronary atherosclerosis. Insulin administration during the induction of atherosclerosis had no effect on the development of lesions. In some experiments, insulin slightly inhibited estrogen-induced protection of the coronary arteries when the birds were on a high cholesterol-oil diet.
- Received January 6, 1960.
- © 1960 American Heart Association, Inc.