Effect of Liver Damage on Experimental Renal Hypertension in the Rat
Renal hypertension was produced in 26 test rats and fell to normal levels when they received CCl4. Our data indicate that this is due to liver damage and not to general inanition. These changes are reversible, since cessation of CCl4 injections led to blood pressure rise. Morphologically, only a moderate degree of fatty metamorphosis is necessary to cause the blood pressure to fall from hypertensive levels to normotension. The biochemical change involved variable changes in albumin and globulin.
- Received December 17, 1959.
- © 1960 American Heart Association, Inc.