Effect of Increased Fibrinogen Concentration on the Lysis of In Vivo Thrombi
The dissolution of clots formed at normal fibrinogen levels and in hyperfibrinogenemia was studied in 10 dogs receiving a standard course of fibrinolytic treatment. A significantly increased resistance of clots formed at high fibrinogen levels to fibrinolytic therapy was found.
- Received November 12, 1959.
- © 1960 American Heart Association, Inc.