Indicator Dilution in an Atrioventricular System with Competent or Incompetent Valves
A Complete Analysis of the Behavior of Indicator Injected Instantaneously or Continuously into Either Chamber
A mathematical analysis of the pumping action of a two-chambered system has been used to develop formulas describing the changes with time in the mass and concentration of an indicator in either chamber of such a system analogous to the atrium and ventricle with either competent or incompetent valves. Such formulas show how the parameters of a system control the shape of an indicator-dilution curve. From these formulas expressions were developed which permit the analysis of the system from an indicator-dilution curve. The theory was then used to analyze dilution curves produced by a model of known parameters.
- Received March 30, 1959.
- © 1959 American Heart Association, Inc.