Perfusion of a Strip of Mammalian Ventricle
Effects of K-Rich and Na-Deficient Solutions on Transmembrane Potentials
A preparation of sheep's or calf's myocardium is described: the m. transversus cordis of the right ventricle. This lends itself to perfusion of its capillary bed as well as to the recording of membrane potentials from single fibers. When the Na concentration in the perfusate is reduced, the action potentials undergo changes that suggest that the "sodium hypothesis" is applicable to cardiac ventricle.
- Received November 24, 1958.
- © 1959 American Heart Association, Inc.