Effect of Nicotinic Acid on the Incorporation of Radiocarbon into Cholesterol
Nicotinic acid when fed to rats as 0.8 per cent of their diet caused an 83 per cent increase in radioactivity of liver cholesterol-digitonin precipitate. In vitro studies using rat liver slices indicated that nicotinic acid increased the incorporation of radiocarbon into cholesterol by 46 per cent.
- Received March 12, 1958.
- © 1958 American Heart Association, Inc.