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Effect of Acute Mitral Insufficiency of Various Degrees on Mean Arterial Blood Pressure, Coronary Blood Flow Cardiac Output and Oxygen Consumption
RENÉ WÉGRIA, GERHARD MUELHEIMS, ROBERT JREISSATY, JIRO NAKANO
https://doi.org/10.1161/01.RES.6.3.301
Circulation Research. 1958;6:301-306
Originally published May 1, 1958RENÉ WÉGRIA
GERHARD MUELHEIMS
ROBERT JREISSATY
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Abstract
In anesthetized dog, acute mitral insufficiency of variable severity results in an increase in coronary blood flow and myocardial oxygen consumption. The increase in oxygen consumption is interpreted as meaning either that the left ventricle expends a significant amount of energy in regurgitating blood into the left atrium during mitral insufficiency, or that mitral insufficiency induces a decrease of the efficiency of the left ventricle or both.
- Received December 26, 1957.
- © 1958 American Heart Association, Inc.
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- Effect of Acute Mitral Insufficiency of Various Degrees on Mean Arterial Blood Pressure, Coronary Blood Flow Cardiac Output and Oxygen ConsumptionRENÉ WÉGRIA, GERHARD MUELHEIMS, ROBERT JREISSATY and JIRO NAKANOCirculation Research. 1958;6:301-306, originally published May 1, 1958https://doi.org/10.1161/01.RES.6.3.301
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- Effect of Acute Mitral Insufficiency of Various Degrees on Mean Arterial Blood Pressure, Coronary Blood Flow Cardiac Output and Oxygen ConsumptionRENÉ WÉGRIA, GERHARD MUELHEIMS, ROBERT JREISSATY and JIRO NAKANOCirculation Research. 1958;6:301-306, originally published May 1, 1958https://doi.org/10.1161/01.RES.6.3.301