Studies of the Effect of Antiarrhythmic Drugs on Carbohydrate Metabolism of Rat Heart Muscle in Vitro
The effect of antiarrhythmic drugs on the oxidation of glucose by heart tissue was studied. Quinine and quinidine inhibited oxygen consumption and glucose utilization by rat heart slices and homogenates, while chloroquine and procaine amide had little effect.
- Received December 10, 1957.
- © 1958 American Heart Association, Inc.