Quantitation of Collagen in Human Myocardium
The collagen concentrations of the four cardiac chambers of normal hearts were determined chemically. Right ventricles and atria contained significantly higher collagen concentrations than did left ventricles and atria. The atria contained twice the collagen concentration of the ventricles. Severe atherosclerosis, hypertrophy and coronary occlusion did not necessarily increase the concentration of collagen in the left ventricle of diseased hearts.
- Received February 25, 1957.
- © 1957 American Heart Association, Inc.