The Effect of Acute Occlusion of the Coronary Sinus on the Coronary Circulation
The changes in the coronary circulation, which are precipitated by the acute occlusion of the coronary sinus, have been investigated. In normal animals, retrograde blood emerging from the peripheral segment of a ligated and transected circumflex coronary artery is small in quantity, and arterial in nature, signifying an insignificant interarterial collateral flow. After the coronary sinus is arterialized, the retrograde circumflex arterial blood increases in quantity and is venous in nature. We now studied the effect on the coronary circulation of elevating the pressure of the coronary sinus by ligation, without arterialization. Under this condition, coronary sinus pressure rises, and retrograde circumflex flow is of normal quantity, but is also venous in nature. The source of this blood from the capillary bed and its directions of flow are discussed.
- Received June 12, 1954.
- © 1954 American Heart Association, Inc.