Errors in the Processing of Dye Dilution Curves
Errors of two kinds occur in the processing of dye dilution curves:
1) Individual estimates of the decay constant of a dye curve are subject to random errors causing a variability of up to 10% in the calculated cardiac output, and of up to 4% in the estimated vascular volume.
2) The use of an inappropriate numerical integration formula can cause an additional error of up to 5% in the calculated cardiac output. This may be avoided by using either the trapezoid rule or Simpson's rule. The planimeter measures areas with sufficient accuracy for routine determination of cardiac output.
- Accepted November 9, 1965.
- © 1966 American Heart Association, Inc.