Pacemaker Periodicity in Atrial Fibrillation
The presence of a periodic component in the atrial waveform of patients with chronic atrial fibrillation can be demonstrated by the use of autocorrelation techniques, and is interpreted as evidence for the presence of a periodic or almost periodic pacemaking mechanism. In twelve patients the average rate of this periodic element was 421 per minute with a range of 346 to 528. No correlation is present between increasing rate and disorder of the waveform.
The presence of persistent random wavelets modifying the beat-to-beat spread of excitation generated by a periodic focal pacemaker is proposed as a unifying hypothesis explaining the variability of the atrial waveform in atrial fibrillation in man.
- Accepted March 23, 1965.
- © 1965 American Heart Association, Inc.