Effect of Coronary Artery Embolization on Ventricular Volumes
The progressive changes in ventricular volumes and pressures created by repeated coronary artery embolizations with lycopodium spores were studied in fifteen intact dogs. In eight of the animals SV increased over control values following the initial embolization. Subsequent embolizations produced a pronounced decrease in SV and SW, an enlarged EDV, and a high ESV/EDV ratio. Left ventricular systolic pressure fell as EDP rose. The progressive increase observed in the ESV/EDV ratio between successive embolizations was the most sensitive functional expression of the deteriorating myocardial performance.
- Accepted November 20, 1964.
- © 1965 American Heart Association, Inc.