Noncompaction in Mitochondrial Disorders
This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
To the Editor:
With interest, we read the article by Towbin and Jefferies about left ventricular noncompaction (LVNC) in patients with inborn errors of metabolism (mitochondrial disorders [MIDs], and storage diseases).1 We have the following comments and concerns.
The authors describe noncompaction in MIDs, such as mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes, myoclonic epilepsy with ragged-red fibers, Kearns–Sayre syndrome, Leigh syndrome, Sengers syndrome, Barth syndrome, and in patients carrying DNAJC19 or TMEM70 mutations.1 However, the number of MIDs presenting with LVNC is larger than presented in this review.2 LVNC has been also described in Leber hereditary optic …