Effects on the Heart of Long-Term Exposure to Obesity
This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
The second half of a man’s life is made up of nothing but the habits he has acquired during the first half.
It is well-documented that obesity, like smoking before it, has reached epidemic proportions. The prevalence of obesity has increased to ≈40% among adults and ≈20% among adolescents.2,3 Furthermore, the cumulative effects of years of excess obesity and abdominal adiposity have been linked to coronary heart disease and heart failure in young adults in the CARDIA study (Coronary Artery Risk Development in Young Adults).4 Increases in heart failure incidence among younger groups and the stagnation of progress in reducing cardiovascular disease mortality have been tied to the obesity epidemic.5–7 If we are going to mirror successes in curbing the smoking epidemic, it will similarly require significant investment in public health policies. To justify this investment and formulate an effective public health strategy, important work is needed to establish how obesity is linked to cardiovascular disease.
Article, see p 1614
Heart failure in particular carries a significant association with obesity. It has been postulated that obesity and excess adiposity necessitate increased cardiac output which leads to increased wall stress and left ventricular (LV) hypertrophy.8 However, it is difficult to tease out whether associated comorbidities such as …