In the Circulation Research article by Jiang et al (Bach1 Represses Wnt/β-Catenin Signaling and Angiogenesis. Circ Res. 2015:117:364–375. DOI: 10.1161/CIRCRESAHA.115.306829), corrections were needed.
In the Results section, two sentences should be corrected as follows: “Bach1 deficiency was also associated with significant increases… in the expression of VEGF (Figure 1D) and a murine functional homologue of IL-8, keratinocyte-derived chemokine (KC) (Figure 1E)….Expression of VEGF and KC…” “Lower levels of Bach1 expression were also associated with significant increases in IL-8, KC, and…”
In the Discussion section, the following changes have been made: “….between IL-8 and Bach1 expression reported here” has been corrected to “between IL-8 (or KC) and Bach1 expression.”
In the Novelty and Significance section, the following changes have been made: “Interleukin 8 and vascular endothelial growth factor are responsible for the antiangiogenic effect of Bach1 on the endothelial cells” has been corrected to “…. on human endothelial cells.”
Also in the Novelty and Significance section, “the expression of interleukin 8 and vascular endothelial growth factor” has been corrected to “the expression of a murine functional homologue of IL-8, keratinocyte-derived chemokine (KC), and vascular endothelial growth factor.”
The y-axes in the charts for Figure 1E and the top left panel of Figure 2D should be changed from “IL-8 mRNA Level” to “KC mRNA Level.” The corresponding text in Figure 1E legend should be corrected to read: “(E) mRNA levels of the murine functional IL-8 homologue keratinocyte-derived chemokine (KC) were…” The corresponding text in Figure 2D legend should be corrected to read: “(D) mRNA or protein levels of IL-8, keratinocyte-derived chemokine (KC), and VEGF…”
In the Online Supplement, the primers used for qRT-PCR analyses of KC expression should be added to Online Table I.
The authors apologize for these errors, and the errors have been noted and corrected in the online version of the article, which is available at http://circres.ahajournals.org/content/117/4/364.full
- © 2015 American Heart Association, Inc.