Production of Ulcerated Atherosclerotic Lesions in Cockerels
1. Ulcerated abdominal aorta and coronary lesions have been produced in cockerels.
2. The prerequisite for ulceration is a lesion previously induced by a high-cholesterol, high-fat, low-protein diet, followed by the administration of large doses of estrogens.
3. The possible mechanisms leading to ulceration have been discussed.
- Received May 1, 1962.
- © 1962 American Heart Association, Inc.