Distribution of 4-Iodoantipyrine After Intravenous Injection in the Rat
The distribution of 4-iodoantipyrine does not parallel that of body water, as evidenced by its overaccumulation in some organs and underaccumulation in others. These disparities occur largely because I131 is lost from the iodoantipyrine molecule, is converted to iodide, and is distributed and excreted as such. Any similarity between the distribution volume of iodoantipyrine and total body water is, therefore, happenstance.
- © 1962 American Heart Association, Inc.