The Effect of a Cholesterol-Free Brain Fraction against Diet-Induced Atherosclerosis
The feeding of a lipid-poor and virtually cholesterol-free residue of mammalian brain mitigates the hypercholesteremia and atherosclerosis ordinarily seen in cholesterol-fed chicks. The probable mechanism depends on the previously demonstrated capacity of oral cerebrosides to convert a large proportion of fecal sterols into unabsorbable coprosterol, thus rendering intestinal cholesterol, unavailable to the body economy.
- Received June 25, 1953.
- © 1953 American Heart Association, Inc.