Basic Science Research

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PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy
Laura X Liu, Glenn C Rowe, Steven Yang, Jian Li, Federico Damilano, Mun Chun Chan, Wenyun Lu, Cholsoon Jang, Shogo Wada, Michael Morley, Michael Hesse, Bernd K Fleischmann, Joshua Rabinowitz, Saumya Das, Anthony Rosenzweig and Zoltan Arany

Circulation Research. 2017;CIRCRESAHA.117.311456, originally published September 19, 2017
https://doi.org/10.1161/CIRCRESAHA.117.311456

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P2Y₂ Nucleotide Receptor Prompts Human Cardiac Progenitor Cell Activation by Modulating Hippo Signaling
Farid G Khalafalla, Steven R Greene, Hashim Khan, Kelli Ilves, Megan M Monsanto, Roberto Alvarez, Monica Chavarria, Jonathan H Nguyen, Benjamin Norman, Walter P Dembitsky and Mark A Sussman

Circulation Research. 2017;CIRCRESAHA.117.310812, originally published September 18, 2017
https://doi.org/10.1161/CIRCRESAHA.117.310812

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CELF1 Mediates Connexin 43 mRNA Degradation in Dilated Cardiomyopathy
Kuei-Ting Chang, Ching-Feng Cheng, Pei-Chih King, Shin-Yi Liu and Guey-Shin Wang

Circulation Research. 2017;CIRCRESAHA.117.311281, originally published September 5, 2017
https://doi.org/10.1161/CIRCRESAHA.117.311281

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TPL2 (Therapeutic Targeting Tumor Progression Locus-2)/ATF4 (Activating Transcription Factor-4)/SDF1α (Chemokine Stromal Cell-Derived Factor-α) Axis Suppresses Diabetic RetinopathyNovelty and Significance
De-Wei Lai, Keng-Hung Lin, Wayne Huey-Herng Sheu, Maw-Rong Lee, Chung-Yu Chen, Wen-Jane Lee, Yi-Wen Hung, Chin-Chang Shen, Tsung-Ju Chung, Shing-Hwa Liu and Meei-Ling Sheu

Circulation Research. 2017;121:e37-e52, originally published July 19, 2017
https://doi.org/10.1161/CIRCRESAHA.117.311066

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EphrinB2 Regulates Cardiac Fibrosis Through Modulating the Interaction of Stat3 and TGF-β/Smad3 SignalingNovelty and Significance
Sheng-an Su, Du Yang, Yue Wu, Yao Xie, Wei Zhu, Zhejun Cai, Jian Shen, Zurong Fu, Yaping Wang, Liangliang Jia, Yidong Wang, Jian-an Wang and Meixiang Xiang

Circulation Research. 2017;121:617-627, originally published July 25, 2017
https://doi.org/10.1161/CIRCRESAHA.117.311045

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SUMOylation Negatively Regulates Angiogenesis by Targeting Endothelial NOTCH SignalingNovelty and Significance
Xiaolong Zhu, Sha Ding, Cong Qiu, Yanna Shi, Lin Song, Yueyue Wang, Yuewen Wang, Jinying Li, Yiran Wang, Yi Sun, Lingfeng Qin, Jun Chen, Michael Simons, Wang Min and Luyang Yu

Circulation Research. 2017;121:636-649, originally published July 31, 2017
https://doi.org/10.1161/CIRCRESAHA.117.310696

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The Myofilament Field Revisited in the Age of Cellular and Molecular Biology
Sakthivel Sadayappan

Circulation Research. 2017;121:601-603, originally published August 31, 2017
https://doi.org/10.1161/CIRCRESAHA.117.311629

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An Unbiased High-Throughput Screen to Identify Novel Effectors That Impact on Cardiomyocyte Aggregate LevelsNovelty and Significance
Patrick M. McLendon, Gregory Davis, James Gulick, Sonia R. Singh, Na Xu, Nathan Salomonis, Jeffery D. Molkentin and Jeffrey Robbins

Circulation Research. 2017;121:604-616, originally published June 27, 2017
https://doi.org/10.1161/CIRCRESAHA.117.310945

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Postnatal Cardiac Gene-Editing Using CRISPR/Cas9 with AAV9-Mediated Delivery of Short Guide RNAs Results in Mosaic Gene Disruption
Anne K Johansen, Bas Molenaar, Danielle Versteeg, Ana R Leitoguinho, Charlotte J Demkes, Bastiaan Spanjaard, Hesther de Ruiter, Farhad A Akbari Moqadam, Lieneke Kooijman, Lorena Zentilin, Mauro Giacca and Eva van Rooij

Circulation Research. 2017;CIRCRESAHA.116.310370, originally published August 29, 2017
https://doi.org/10.1161/CIRCRESAHA.116.310370

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Activation of γ2-AMPK Suppresses Ribosome Biogenesis and Protects Against Myocardial Ischemia/Reperfusion Injury
Yang Cao, Naveen Bojjireddy, Maengjo Kim, Tao Li, Peiyong Zhai, Narayani Nagarajan, Junichi Sadoshima, Richard D Palmiter and Rong Tian

Circulation Research. 2017;CIRCRESAHA.117.311159, originally published August 23, 2017
https://doi.org/10.1161/CIRCRESAHA.117.311159

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