ACE/Angiotensin Receptors/Renin Angiotensin System

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Clinical Relevance and Role of Neuronal AT₁ Receptors in ADAM17-Mediated ACE2 Shedding in Neurogenic HypertensionNovelty and Significance
Jiaxi Xu, Srinivas Sriramula, Huijing Xia, Lisa Moreno-Walton, Frank Culicchia, Oliver Domenig, Marko Poglitsch and Eric Lazartigues

Circulation Research. 2017;121:43-55, originally published May 16, 2017
https://doi.org/10.1161/CIRCRESAHA.116.310509

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Loss of Smooth Muscle α-Actin Leads to NF-κB–Dependent Increased Sensitivity to Angiotensin II in Smooth Muscle Cells and Aortic EnlargementNovelty and Significance
Jiyuan Chen, Andrew Peters, Christina L. Papke, Carlos Villamizar, Lea-Jeanne Ringuette, Jiumei Cao, Shanzhi Wang, Shuangtao Ma, Limin Gong, Katerina L. Byanova, Jian Xiong, Michael X. Zhu, Rosalinda Madonna, Patrick Kee, Yong-Jian Geng, Allan R. Brasier, Elaine C. Davis, Siddharth Prakash, Callie S. Kwartler and Dianna M. Milewicz

Circulation Research. 2017;120:1903-1915, originally published May 1, 2017
https://doi.org/10.1161/CIRCRESAHA.117.310563

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Aging, Smooth Muscle Vitality, and Aortic Integrity
Jay D. Humphrey and Dianna M. Milewicz

Circulation Research. 2017;120:1849-1851, originally published June 8, 2017
https://doi.org/10.1161/CIRCRESAHA.117.311075

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The High Blood Pressure-Malaria Protection HypothesisNovelty and Significance
Julio Gallego-Delgado, Thomas Walther and Ana Rodriguez

Circulation Research. 2016;119:1071-1075, originally published September 22, 2016
https://doi.org/10.1161/CIRCRESAHA.116.309602

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Angiotensin II–Linked Hypothesis to Understand the Advantage of the Coevolution of Hypertension and Malaria“Sympathy for the Devil”
Massimo Volpe, Allegra Battistoni and Giuseppe Mancia

Circulation Research. 2016;119:1046-1048, originally published October 27, 2016
https://doi.org/10.1161/CIRCRESAHA.116.309855

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Letter by Zhou and Zhou Regarding Article, “Hypertension: Renin–Angiotensin–Aldosterone System Alterations”
Shi-Sheng Zhou and Yiming Zhou

Circulation Research. 2016;119:e104, originally published September 1, 2016
https://doi.org/10.1161/CIRCRESAHA.116.309472

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Canon Fodder—A Case for Contrarian Science
Gerald W. Dorn

Circulation Research. 2016;119:584-586, originally published August 18, 2016
https://doi.org/10.1161/CIRCRESAHA.116.309519

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AT₂ Receptor Activation Prevents Sodium Retention and Reduces Blood Pressure in Angiotensin II–Dependent HypertensionNovelty and Significance
Brandon A. Kemp, Nancy L. Howell, Susanna R. Keller, John J. Gildea, Shetal H. Padia and Robert M. Carey

Circulation Research. 2016;119:532-543, originally published June 20, 2016
https://doi.org/10.1161/CIRCRESAHA.116.308384

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Role of the ACE2/Angiotensin 1–7 Axis of the Renin–Angiotensin System in Heart Failure
Vaibhav B. Patel, Jiu-Chang Zhong, Maria B. Grant and Gavin Y. Oudit

Circulation Research. 2016;118:1313-1326, originally published April 14, 2016
https://doi.org/10.1161/CIRCRESAHA.116.307708

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Duchenne Muscular Dystrophy Mice and MenCan Understanding a Genetic Cardiomyopathy Inform Treatment of Other Myocardial Diseases?
Jill A. Rafael-Fortney, Jessica A. Chadwick and Subha V. Raman

Circulation Research. 2016;118:1059-1061, originally published March 31, 2016
https://doi.org/10.1161/CIRCRESAHA.116.308402

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