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(Circulation Research. 2003;92:1057.)
© 2003 American Heart Association, Inc.

Editorials

Circulation Research

The Impact of a Journal and Its Editor on a Career in Experimental Cardiology

Robert B. Jennings

From the Department of Pathology, Duke University Medical Center, Durham, NC.

Correspondence to Robert B. Jennings, MD, Department of Pathology, Box 3712, 409 Elf St, Duke University Medical Center, Durham, NC 27710. E-mail jenni004@mc.duke.edu

Key Words: fiftieth anniversary • impact factor • clinical cardiology • American Heart Association • irreversible injury

An extract of the first 250 words of the full text is provided, because this article has no abstract.

In the early 1950s, the leadership of the American Heart Association recognized that much more fundamental knowledge of basic cardiovascular function was required if one was going to improve the treatment and diagnosis of heart disease. They believed that a journal dedicated to basic research on the circulation would foster an increased understanding of the cardiovascular system and founded Circulation Research. In 1953, when volume 1 of Circulation Research was published, the basic sciences relevant to cardiovascular research such as physiology, biochemistry, pharmacology, and pathology all had journals that were devoted to these disciplines in which there were scattered studies on the heart and circulation. However, these studies were not always read by basic scientists in other disciplines, and the field lacked a journal devoted primarily to understanding how the cardiovascular system worked in health and disease. Circulation Research provided a forum where studies on the heart and cardiovascular system could be published and has been eminently successful in fostering the application of the basic medical sciences to understanding the function of the cardiovascular system.

At the time the journal was founded, basic research support was beginning to be available from the National Institutes of Health, and basic knowledge of biology was being developed at an enormous rate, but from meager foundations. Mitochondria had moved from objects difficult to discern by histological techniques to organelles of considerable interest to biochemists. Moreover, methods of isolating them from heart and studying their metabolism were under development. Energy metabolism in general, the . . . [Full Text of this Article]