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Circulation Research. 2008;102:16-31
doi: 10.1161/CIRCRESAHA.107.164186
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(Circulation Research. 2008;102:16.)
© 2008 American Heart Association, Inc.

Review

Forkhead Transcription Factors and Cardiovascular Biology

Kyriakos N. Papanicolaou, Yasuhiro Izumiya, Kenneth Walsh

From Molecular Cardiology, Whitaker Cardiovascular Institute, Boston University School of Medicine, Mass.

Correspondence to Kenneth Walsh, PhD, Molecular Cardiology/Whitaker Cardiovascular Institute, Boston University School of Medicine, 715 Albany Street, W611, Boston, MA 02118. E-mail kxwalsh{at}bu.edu

This Review is part of a thematic series on Transcription Factors, which includes the following articles:

Regulation of Vascular Inflammation and Remodeling by ETS Factors

Myocardin-Related Transcription Factors: Critical Coactivators Regulating

Cardiovascular Development and Adaptation

Notch Signaling in Blood Vessels: Who is Talking to Whom About What?

Role of Krüppel-like transcription factors in Endothelial Biology

Forkhead Transcription Factors and Cardiovascular Biology

Epigenetic regulation of Vascular Endothelial Gene Expression
Mukesh Jain Guest Editor

The Forkhead family of transcription factors modulates a wide variety of cellular functions in cardiovascular tissues. In this review article, we discuss recent advances in our understanding of regulation provided by the forkhead factors in cardiac myocytes and vascular cells.


Key Words: angiogenesis • endothelial cells • forkhead • transcription factors • vascular biology




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