Dynamic and Neurogenic Factors Determining the Hepatic Arterial Flow after Portal Occlusion

¹ Department of Physiology, Western Reserve University School of Medicine, Cleveland, Ohio

Acute ligation of the portal vein in the barbital-anesthetized dog produces a significant increase in the hepatic arterial flow when the perfusion pressure remains elevated in the artery. Evidence is presented which supports the concept that the immediate readjustment is solely dependent on dynamic changes. The late readjustments are probably conditioned by the interplay of neurogenic and humoral factors.