Correction
for
Ying et al., Circ Res 79 (4) 898-908.
Circulation Research. 1996;79:1218
(Circulation Research. 1996;79:1218.)
© 1996 American Heart Association, Inc.
Corrections
In the article by Ying et al, "Ca
2+ waves in lung capillary
endothelium" (
Circ Res. 1996;79:898-908), on page 903, the paragraph
headed "Wave Velocity" should read "We calculated a propagation
velocity (v) of the
intercellular Ca
2+ wave of 5±2 µm/s
(n=9) from the wave-velocity equation v=2
fd/
, using values for
intercellular phase delay (
) of the dominant wave component
at frequency f and internuclear distance d, between adjoining
cells." (Emphasis added.) Also, the first sentence of the legend
for Figure 5 should read as follows: "Endothelial [Ca
2+]
i profiles
for a single lung capillary are shown during periods of capillary
perfusion with blood or with Ca
2+-free dextran-Ringer (dextran
in Ca
2+-free buffer containing
0.5 mmol/L EGTA)." (Emphasis
added.) The concentration was stated correctly in the text.
In the article by Bernstein et al, "Function and production of nitric oxide in the coronary circulation of the conscious dog during exercise" (Circ Res. 1996;79:840-848), on page 846, two x-axis labels for Figures 3 and 4 were omitted by printer error. The figures are correctly reproduced below.
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Figure 3. The relationship between myocardial oxygen consumption (MVO2) and myocardial work. MVO2 was calculated as the arterial-CS oxygen difference multiplied by mean CBF, and myocardial work (A) was estimated by the triple product (LV systolic pressure times LV dP/dt times heart rate, in millions). Both MVO2 and the triple product increased with exercise in a linear fashion (y=0.11x+5.1; R2=.96) in the normal state. After blockade of NO synthesis with NLA, there was a significant elevation in the slope (n=15, P<.05) of this relationship (y=0.15x+5.3; R2=.98). When MVO2 is compared with cardiac minute work (pressure-volume loop area multiplied by heart rate) (B), a similar effect is revealed. Blockade of NO synthesis increases the slope of the work–oxygen consumption relationship (n=5, P<.05). The triple product was compared with cardiac minute work (C), and the two are linearly related.
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Figure 4. CS NOX levels before (triangles) and after (circles) blockade of NO synthesis with NLA (A). NOX release was calculated as the difference between the arterial and CS plasma NOX (B). There was a significant release of NOX during exercise. After NLA, there was a significant reduction in NOX release, reaching a value that was not different from zero. NOX production (NOX release multiplied by mean CBF) increased significantly with exercise and was abolished with NLA (C). *P<.05 vs zero; **P<.05 vs rest; and #P<.05 vs pre-NLA (normal).
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