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(Circulation Research. 2006;98:e67.)
© 2006 American Heart Association, Inc.

Letters to the Editor

Angiopoietin and Vascular Remodeling: The Data at Face Value

Shirley H.J. Mei

Institute of Medical Science, University of Toronto, Division of Cardiology, Department of Medicine, St. Michael’s Hospital

Duncan J. Stewart

Dexter Man Chair, University of Toronto, McLaughlin Centre for Molecular Medicine, Division of Cardiology, Department of Medicine, St. Michael’s Hospital, Toronto, Ontario, Canada

We read with great interest the recent report by Cho et al in a July issue of Circulation Research.¹ However, we were struck by a remarkable feature in a Figure 1B of their article, reproduced here in the accompanying Figure (panel I). In the upper right corner there is the unmistakable resemblance to a human face, albeit with a somewhat skeletal appearance. But what is even more surprising is that a very similar face is clearly visible in the lower right panel of their Figure 3B, reproduced here in panel II, even though this image is representative of a different animal that was studied in a separate experiment. A closer examination reveals that not only is this very same ghostly face seen in the previous image, but that the vasculature architecture in these two figures is also identical, apart from slight horizontal compression. The facial resemblance can be even better appreciated after enlargement of the region within the box (panel III). We would thus submit that there has been an inadvertent duplication of this figure, and one of these images has been erroneously reproduced. Therefore, we would respectfully ask the authors to face the facts, do an about face, and correct this ghostly error!

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References

1. Cho CH, Kim KE, Byun J, Jang HS, Kim DK, Baluk P, Baffert F, Lee GM, Mochizuki N, Kim J, Jeon BH, McDonald DM, Koh GY. Long-term and sustained COMP-Ang1 induces long-lasting vascular enlargement and enhanced blood flow. Circ Res. 2005; 97: 86–94.[Abstract/Free Full Text]

This Article Extract Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Mei, S. H.J. Articles by Stewart, D. J. Search for Related Content PubMed PubMed Citation Articles by Mei, S. H.J. Articles by Stewart, D. J.