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Circulation Research. 2005;96:939-949
doi: 10.1161/01.RES.0000163635.62927.34
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(Circulation Research. 2005;96:939.)
© 2005 American Heart Association, Inc.


Reviews

Adipose Tissue, Inflammation, and Cardiovascular Disease

Anders H. Berg, Philipp E. Scherer

From the Departments of Cell Biology (A.H.B., P.E.S.), Medicine (P.E.S.), Division of Endocrinology, and Diabetes Research and Training Center (P.E.S.), Albert Einstein College of Medicine, Bronx, NY. A.H. Berg’s present address: Department of Pathology, Brigham and Women’s Hospital, 75 Francis St, Boston, MA 02115.

Correspondence to Philipp E. Scherer, Albert Einstein College of Medicine 1300 Morris Park Ave, Bronx, NY 10461. E-mail scherer{at}aecom.yu.edu

This Review is part of a thematic series on Adipocyte Signaling in the Cardiovascular System, which includes the following articles:

Adipose Tissue, Inflammation, and Cardiovascular Disease

Diabetic Cardiomyopathy

Adipocyte Signaling and Lipid Homeostasis

Adipocyte Signaling and the Vasculature

PPAR{gamma} Activation and Effects on the Vasculature
Philipp E. Scherer Guest Editor

Mounting evidence highlights the role of adipose tissue in the development of a systemic inflammatory state that contributes to obesity-associated vasculopathy and cardiovascular risk. Circulating mediators of inflammation participate in the mechanisms of vascular insult and atheromatous change, and many of these inflammatory proteins are secreted directly from adipocytes and adipose tissue–derived macrophages. Several factors linking obesity with an increased cardiovascular risk have been identified. The adipocyte-specific secretory protein adiponectin is a particularly promising candidate in this context. Its levels are decreased in obesity. Adiponectin may mediate some of its demonstrated cardioprotective effects through its anti-inflammatory properties. In addition to decreased expression of beneficial adipokines, secretion of a host of inflammatory factors from visceral adipose tissue may contribute to the increased cardiovascular risk associated with obesity. The cardioprotective effects of many of the most popular drug regimens corroborate these conclusions, demonstrating that along with improvements in other therapeutic end points, they mediate improvements in systemic inflammation. In some cases, these improvements are attributable to direct suppression of inflammatory signaling in adipocytes. The targeted suppression of various proinflammatory cascades in adipocytes specifically represents an exciting new therapeutic opportunity for the cardiovascular disease area.


Key Words: adipocyte • secretion • inflammation




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[Abstract] [Full Text] [PDF]


Home page
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[Abstract] [Full Text] [PDF]


Home page
Eur J EndocrinolHome page
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[Abstract] [Full Text] [PDF]


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[Abstract] [Full Text] [PDF]


Home page
Arterioscler. Thromb. Vasc. Bio.Home page
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[Abstract] [Full Text] [PDF]


Home page
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[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
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[Abstract] [Full Text] [PDF]


Home page
J. Am. Soc. Nephrol.Home page
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J. Am. Soc. Nephrol., March 1, 2008; 19(3): 593 - 599.
[Abstract] [Full Text] [PDF]


Home page
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Circ. Res., February 1, 2008; 102(2): 140 - 142.
[Full Text] [PDF]


Home page
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Hypertension, January 1, 2008; 51(1): 8 - 14.
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Home page
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Home page
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Circulation, November 13, 2007; 116(20): 2275 - 2279.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
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J. Clin. Endocrinol. Metab., November 1, 2007; 92(11): 4366 - 4372.
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Home page
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Arterioscler. Thromb. Vasc. Biol., November 1, 2007; 27(11): 2284 - 2291.
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Therapeutic Advances in Cardiovascular Disease, October 1, 2007; 1(1): 61 - 81.
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Home page
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Effect of acute hyperinsulinaemia with and without angiotensin II type 1 receptor blockade on resistin and adiponectin concentrations and expressions in healthy subjects
Eur. J. Endocrinol., October 1, 2007; 157(4): 443 - 449.
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Home page
Am. J. Clin. Nutr.Home page
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Home page
J. Biol. Chem.Home page
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J. Biol. Chem., August 31, 2007; 282(35): 25445 - 25452.
[Abstract] [Full Text] [PDF]


Home page
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Endocr. Rev., August 1, 2007; 28(5): 463 - 491.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
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[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
M. Cesari, K. Narkiewicz, R. De Toni, E. Aldighieri, C. J. Williams, and G. P. Rossi
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J. Clin. Endocrinol. Metab., August 1, 2007; 92(8): 3082 - 3088.
[Abstract] [Full Text] [PDF]


Home page
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Diabetes Care, August 1, 2007; 30(8): 2145 - 2147.
[Full Text] [PDF]


Home page
Am. J. Physiol. Cell Physiol.Home page
Y. Y. Sautin, T. Nakagawa, S. Zharikov, and R. J. Johnson
Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress
Am J Physiol Cell Physiol, August 1, 2007; 293(2): C584 - C596.
[Abstract] [Full Text] [PDF]


Home page
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J. F. Arenillas, M. A. Moro, and A. Davalos
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Stroke, July 1, 2007; 38(7): 2196 - 2203.
[Full Text] [PDF]


Home page
Cardiovasc ResHome page
R. Palanivel, X. Fang, M. Park, M. Eguchi, S. Pallan, S. De Girolamo, Y. Liu, Y. Wang, A. Xu, and G. Sweeney
Globular and full-length forms of adiponectin mediate specific changes in glucose and fatty acid uptake and metabolism in cardiomyocytes
Cardiovasc Res, July 1, 2007; 75(1): 148 - 157.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
K. Fujimori, K. Aritake, and Y. Urade
A Novel Pathway to Enhance Adipocyte Differentiation of 3T3-L1 Cells by Up-regulation of Lipocalin-type Prostaglandin D Synthase Mediated by Liver X Receptor-activated Sterol Regulatory Element-binding Protein-1c
J. Biol. Chem., June 22, 2007; 282(25): 18458 - 18466.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
K. K. Koh, M. J. Quon, Y. Lee, S. H. Han, J. Y. Ahn, W.-J. Chung, J.-a Kim, and E. K. Shin
Additive beneficial cardiovascular and metabolic effects of combination therapy with ramipril and candesartan in hypertensive patients
Eur. Heart J., June 2, 2007; 28(12): 1440 - 1447.
[Abstract] [Full Text] [PDF]


Home page
Cardiovasc ResHome page
O. Grisk
Apelin and vascular dysfunction in type 2 diabetes
Cardiovasc Res, June 1, 2007; 74(3): 339 - 340.
[Full Text] [PDF]


Home page
Arch Intern MedHome page
X. Zhang, X.-O. Shu, G. Yang, H. Li, H. Cai, Y.-T. Gao, and W. Zheng
Abdominal Adiposity and Mortality in Chinese Women
Arch Intern Med, May 14, 2007; 167(9): 886 - 892.
[Abstract] [Full Text] [PDF]


Home page
J. Dent. Res.Home page
N. Pischon, N. Heng, J.-P. Bernimoulin, B.-M. Kleber, S.N. Willich, and T. Pischon
Obesity, Inflammation, and Periodontal Disease
J. Dent. Res., May 1, 2007; 86(5): 400 - 409.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
C. Tsioufis, K. Dimitriadis, M. Selima, C. Thomopoulos, C. Mihas, I. Skiadas, D. Tousoulis, C. Stefanadis, and I. Kallikazaros
Low-grade inflammation and hypoadiponectinaemia have an additive detrimental effect on aortic stiffness in essential hypertensive patients
Eur. Heart J., May 1, 2007; 28(9): 1162 - 1169.
[Abstract] [Full Text] [PDF]


Home page
Arterioscler. Thromb. Vasc. Bio.Home page
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Arterioscler. Thromb. Vasc. Biol., May 1, 2007; 27(5): 996 - 1003.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Endocrinol. Metab.Home page
J. Zhang, W. Wright, D. A. Bernlohr, S. W. Cushman, and X. Chen
Alterations of the classic pathway of complement in adipose tissue of obesity and insulin resistance
Am J Physiol Endocrinol Metab, May 1, 2007; 292(5): E1433 - E1440.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
R. S. Beaser and P. Levy
A Work in Progress, but a Useful Construct
Circulation, April 3, 2007; 115(13): 1812 - 1818.
[Full Text] [PDF]


Home page
DiabetesHome page
E. Chevillotte, M. Giralt, B. Miroux, D. Ricquier, and F. Villarroya
Uncoupling Protein-2 Controls Adiponectin Gene Expression in Adipose Tissue Through the Modulation of Reactive Oxygen Species Production
Diabetes, April 1, 2007; 56(4): 1042 - 1050.
[Abstract] [Full Text] [PDF]


Home page
Cardiovasc ResHome page
T. A. Hopkins, N. Ouchi, R. Shibata, and K. Walsh
Adiponectin actions in the cardiovascular system
Cardiovasc Res, April 1, 2007; 74(1): 11 - 18.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
A. Xu, A. W.K. Tso, B. M.Y. Cheung, Y. Wang, N. M.S. Wat, C. H.Y. Fong, D. C.Y. Yeung, E. D. Janus, P. C. Sham, and K. S.L. Lam
Circulating Adipocyte-Fatty Acid Binding Protein Levels Predict the Development of the Metabolic Syndrome: A 5-Year Prospective Study
Circulation, March 27, 2007; 115(12): 1537 - 1543.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
K. Kos, A. L. Harte, N. F. da Silva, A. Tonchev, G. Chaldakov, S. James, D. R. Snead, B. Hoggart, J. P. O'Hare, P. G. McTernan, et al.
Adiponectin and Resistin in Human Cerebrospinal Fluid and Expression of Adiponectin Receptors in the Human Hypothalamus
J. Clin. Endocrinol. Metab., March 1, 2007; 92(3): 1129 - 1136.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
T. B. Dahl, A. Yndestad, M. Skjelland, E. Oie, A. Dahl, A. Michelsen, J. K. Damas, S. H. Tunheim, T. Ueland, C. Smith, et al.
Increased Expression of Visfatin in Macrophages of Human Unstable Carotid and Coronary Atherosclerosis: Possible Role in Inflammation and Plaque Destabilization
Circulation, February 27, 2007; 115(8): 972 - 980.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
S. H. Han, M. J. Quon, J.-a Kim, and K. K. Koh
Adiponectin and Cardiovascular Disease: Response to Therapeutic Interventions
J. Am. Coll. Cardiol., February 6, 2007; 49(5): 531 - 538.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
T. Pischon and E. B. Rimm
Adiponectin and risk of acute coronary syndromes: defining the obesity phenotype
Eur. Heart J., February 1, 2007; 28(3): 274 - 275.
[Full Text] [PDF]


Home page
J. Appl. Physiol.Home page
S. A. Shore
Obesity and asthma: lessons from animal models
J Appl Physiol, February 1, 2007; 102(2): 516 - 528.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
J. D. Brown and J. Plutzky
Peroxisome Proliferator Activated Receptors as Transcriptional Nodal Points and Therapeutic Targets
Circulation, January 30, 2007; 115(4): 518 - 533.
[Abstract] [Full Text] [PDF]


Home page
Arterioscler. Thromb. Vasc. Bio.Home page
T. Suganami, K. Tanimoto-Koyama, J. Nishida, M. Itoh, X. Yuan, S. Mizuarai, H. Kotani, S. Yamaoka, K. Miyake, S. Aoe, et al.
Role of the Toll-like Receptor 4/NF-{kappa}B Pathway in Saturated Fatty Acid-Induced Inflammatory Changes in the Interaction Between Adipocytes and Macrophages
Arterioscler. Thromb. Vasc. Biol., January 1, 2007; 27(1): 84 - 91.
[Abstract] [Full Text] [PDF]


Home page
Clin. Chem.Home page
Y. Wang, K. S. L. Lam, E. W. Kraegen, G. Sweeney, J. Zhang, A. W.K. Tso, W.-S. Chow, N. M.S. Wat, J. Y. Xu, R. L.C. Hoo, et al.
Lipocalin-2 Is an Inflammatory Marker Closely Associated with Obesity, Insulin Resistance, and Hyperglycemia in Humans
Clin. Chem., January 1, 2007; 53(1): 34 - 41.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Endocrinol. Metab.Home page
C. N. Lumeng, S. M. Deyoung, and A. R. Saltiel
Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins
Am J Physiol Endocrinol Metab, January 1, 2007; 292(1): E166 - E174.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Endocrinol. Metab.Home page
M. Cardellini, M. A. Marini, S. Frontoni, M. L. Hribal, F. Andreozzi, F. Perticone, M. Federici, D. Lauro, and G. Sesti
Carotid artery intima-media thickness is associated with insulin-mediated glucose disposal in nondiabetic normotensive offspring of type 2 diabetic patients
Am J Physiol Endocrinol Metab, January 1, 2007; 292(1): E347 - E352.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
L. Qiao and J. Shao
SIRT1 Regulates Adiponectin Gene Expression through Foxo1-C/Enhancer-binding Protein {alpha} Transcriptional Complex
J. Biol. Chem., December 29, 2006; 281(52): 39915 - 39924.
[Abstract] [Full Text] [PDF]


Home page
Endocr. Rev.Home page
M. E. Trujillo and P. E. Scherer
Adipose Tissue-Derived Factors: Impact on Health and Disease
Endocr. Rev., December 1, 2006; 27(7): 762 - 778.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
R. T. de Jongh, R. G. Ijzerman, E. H. Serne, J. J. Voordouw, J. S. Yudkin, H. A. D.-v. de Waal, C. D. A. Stehouwer, and M. M. van Weissenbruch
Visceral and Truncal Subcutaneous Adipose Tissue Are Associated with Impaired Capillary Recruitment in Healthy Individuals
J. Clin. Endocrinol. Metab., December 1, 2006; 91(12): 5100 - 5106.
[Abstract] [Full Text] [PDF]


Home page
DiabetesHome page
Z. H. Huang, C. A. Reardon, and T. Mazzone
Endogenous ApoE Expression Modulates Adipocyte Triglyceride Content and Turnover
Diabetes, December 1, 2006; 55(12): 3394 - 3402.
[Abstract] [Full Text] [PDF]