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(Circulation Research. 2003;93:1146.)
© 2003 American Heart Association, Inc.

Reviews

Noninvasive Imaging of Myocardial Viability

Current Techniques and Future Developments

Katherine C. Wu, João A.C. Lima

From the Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Md.

Correspondence to Dr João A.C. Lima, The Johns Hopkins Medical Institutions, Division of Cardiology, Department of Medicine, Carnegie 568, 600 N Wolfe St, Baltimore, MD 21287. E-mail jlima{at}jhmi.edu

This Review is part of a thematic series on Biological Imaging of the Cardiovascular System, which includes the following articles:

Noninvasive Imaging of Myocardial Viability: Current Techniques and Future Developments
Imaging Neovascular Growth
Seeing Within: Molecular Imaging of the Cardiovascular System
Emerging Imaging Techniques

Elliot R. McVeigh Guest Editor

Complete knowledge of myocardial structure, metabolism, and function is crucial to understanding the response of the heart to injury such as ischemia. Increasingly, this type of knowledge is required at multiple levels, from that of the isolated myocyte to the functioning organism, to provide basic scientists and clinical investigators a common framework for translation of findings and information feedback. This article focuses on the utilization of imaging methods to assess myocardial viability in vivo. It discusses the advantages and pitfalls of different imaging techniques, with particular emphasis on available data in humans and large animal models. Because of their novelty and potential for accurate phenotyping of human pathophysiology, magnetic resonance modalities will be highlighted.

Key Words: cardiac magnetic resonance imaging • myocardial viability • myocardial metabolism

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