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Circulation Research. 1956;4:488-492

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(Circulation Research. 1956;4:488.)
© 1956 American Heart Association, Inc.

Partial Separation of an Oxytocic Principle from Preparations of Angiotonin

F. MERLIN BUMPUS PH.D.1, HANS SCHWARZ PH.D.1, IRVINE H. PAGE M.D.1

1 Research Division of the Cleveland Clinic Foundation and the Frank E. Bunts Educational Institute, Cleveland, Ohio

Partially purified angiotonin preparations have been shown to contain both oxytocic and pressor activity. However, they do not parallel each other in samples of differing purity. Methods for their partial separation and purification are described.

Submitted on April 2, 1956




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F. M. BUMPUS, H. SCHWARZ, and I. H. PAGE
Synthesis and Pharmacology of the Octapeptide Angiotonin
Science, May 3, 1957; 125(3253): 886 - 887.
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