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Circulation Research. 1956;4:263-267

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(Circulation Research. 1956;4:263.)
© 1956 American Heart Association, Inc.

Histochemical Evaluation of Canine Coronary Artery and Aortic Lesions Induced by Intravenous Allylamine

L. L. CONRAD M.D.1, I. E. GONZALEZ PH.D.1, W. JOEL M.D.1, R. H. FURMAN M.D.1

1 Cardiovascular Section, Oklahoma Medical Research Institute and the Departments of Medicine, Pathology and Anatomy, University of Oklahoma School of Medicine Oklahoma City, Okla

The early lesions of the coronary arteries and aorta in animals given intravenous allylamine are described and are noted to be characterized by glycogen accumulation and by ground substance change indicated by increased PAS-positive material present after incubation with diastase. It is suggested that heterogeneous polysaccharides and/or substances containing 1-2 glycol linkages, other than sulphated acid polysaccharides, may be of importance in the early lesion.

Submitted on January 3, 1956




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