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Circulation Research. 1962;10:473-490

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(Circulation Research. 1962;10:473.)
© 1962 American Heart Association, Inc.

Indicator-Dilution Studies with "Diffusible" Indicators

Francis P. Chinard M.D.1, Theodore Enns Ph.D.1, Mary F. Nolan B.A.1

1 The Departments of Physiological Chemistry and Medicine, The Johns Hopkins University School of Medicine; The Division of Medicine, The Baltimore City Hospitals, Baltimore, Maryland

Some of the applications and extensions of the indicator-dilution technics have been presented. The technics offer possibilities for the investigation of some of the parameters of the circulatory and respiratory systems. They also offer a means of studying some of the more rapid features of organ metabolism in vivo. Compared to the degree of sophistication achieved by the more conventional dye-dilution studies, these extensions with "diffusible" indicators are in an embryonic stage of development. It is believed that they have a future.




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