Further Evidence for a Critical Vessel Caliber in Experimental Coronary Shock

¹ Cardiovascular Laboratory, General Medical Research Service of the Veterans Administration Center, and the Departments of Medicine and Anatomy, University of California Medical Center Los Angeles, Calif

New experiments confirm previous observations that production of protracted coronary shock in the closed-chest dog following microsphere embolization is a critical function of the embolus size. The vessels occluded by the critical emboli have been located by a plastic coronary injection-tissue corrosion technic, and a definite relationship has been demonstrated between vessel caliber and anatomic type, in a dog heart, for the gradient from epicardium through endocardium.