Animal models of human disease

Citations 341-350 of 1172 total displayed.

Past content (since Jan 1999):

Molecular Medicine
Disruption of Planar Cell Polarity Signaling Results in Congenital Heart Defects and Cardiomyopathy Attributable to Early Cardiomyocyte Disorganization: Helen M. Phillips, Hong Jun Rhee, Jennifer N. Murdoch, Victoria Hildreth, Jonathan D. Peat, Robert H. Anderson, Andrew J. Copp, Bill Chaudhry, and Deborah J. Henderson
Circ. Res. 2007;101:137-145; published online before print as doi:10.1161/CIRCRESAHA.106.142406 [Abstract] [Full text]

Molecular Medicine
Yin Yang-1 Inhibits Vascular Smooth Muscle Cell Growth and Intimal Thickening by Repressing p21^WAF1/Cip1 Transcription and p21^WAF1/Cip1-Cdk4-Cyclin D1 Assembly: Fernando S. Santiago, Hideto Ishii, Shahida Shafi, Rohit Khurana, Peter Kanellakis, Ravinay Bhindi, Manfred J. Ramirez, Alexander Bobik, John F. Martin, Colin N. Chesterman, Ian C. Zachary, and Levon M. Khachigian
Circ. Res. 2007;101:146-155; published online before print as doi:10.1161/CIRCRESAHA.106.145235 [Abstract] [Full text]

Integrative Physiology
Knock-In Mouse Model of Dilated Cardiomyopathy Caused by Troponin Mutation: Cheng-Kun Du, Sachio Morimoto, Kiyomasa Nishii, Reiko Minakami, Mika Ohta, Naoto Tadano, Qun-Wei Lu, Yuan-Yuan Wang, Dong-Yun Zhan, Misato Mochizuki, Satomi Kita, Yoshikazu Miwa, Fumi Takahashi-Yanaga, Takahiro Iwamoto, Iwao Ohtsuki, and Toshiyuki Sasaguri
Circ. Res. 2007;101:185-194; published online before print as doi:10.1161/CIRCRESAHA.106.146670 [Abstract] [Full text]

Integrative Physiology
Augmented Protein Kinase C- ${alpha}$ –Induced Myofilament Protein Phosphorylation Contributes to Myofilament Dysfunction in Experimental Congestive Heart Failure: Rashad J. Belin, Marius P. Sumandea, Edward J. Allen, Kelly Schoenfelt, Helen Wang, R. John Solaro, and Pieter P. de Tombe
Circ. Res. 2007;101:195-204; published online before print as doi:10.1161/CIRCRESAHA.107.148288 [Abstract] [Full text]

Integrative Physiology
Dilated Cardiomyopathy Mutant Tropomyosin Mice Develop Cardiac Dysfunction With Significantly Decreased Fractional Shortening and Myofilament Calcium Sensitivity: Sudarsan Rajan, Rafeeq P.H. Ahmed, Ganapathy Jagatheesan, Natalia Petrashevskaya, Greg P. Boivin, Dalia Urboniene, Grace M. Arteaga, Beata M. Wolska, R. John Solaro, Stephen B. Liggett, and David F. Wieczorek
Circ. Res. 2007;101:205-214; published online before print as doi:10.1161/CIRCRESAHA.107.148379 [Abstract] [Full text]

Articles Loss of Elastic Fiber Integrity and Reduction of Vascular Smooth Muscle Contraction Resulting From the Upregulated Activities of Matrix Metalloproteinase-2 and -9 in the Thoracic Aortic Aneurysm in Marfan Syndrome: Ada W.Y. Chung, Karen Au Yeung, George G.S. Sandor, Daniel P. Judge, Harry C. Dietz, and Cornelis van Breemen
Circ. Res. published July 19, 2007, doi:10.1161/CIRCRESAHA.107.157776 [Abstract]

Articles
Electrophysiological Maturation and Integration of Murine Fetal Cardiomyocytes After Transplantation: Marcel Halbach, Kurt Pfannkuche, Frank Pillekamp, Agnieszka Ziomka, Tobias Hannes, Michael Reppel, Juergen Hescheler, and Jochen Müller-Ehmsen
Circ. Res. published July 19, 2007, doi:10.1161/CIRCRESAHA.107.153643 [Abstract]

Articles
Identification of Pathways for Atherosclerosis in Mice Integration of Quantitative Trait Locus Analysis and Global Gene Expression Data: Susanna S. Wang, Eric E. Schadt, Hui Wang, Xuping Wang, Leslie Ingram-Drake, Weibin Shi, Thomas A. Drake, and Aldons J. Lusis
Circ. Res. published July 19, 2007, doi:10.1161/CIRCRESAHA.107.152975 [Abstract]

Molecular Medicine
RhoGDI-1 Modulation of the Activity of Monomeric RhoGTPase RhoA Regulates Endothelial Barrier Function in Mouse Lungs: Matvey Gorovoy, Radu Neamu, Jiaxin Niu, Stephen Vogel, Dan Predescu, Jun Miyoshi, Yoshimi Takai, Vidisha Kini, Dolly Mehta, Asrar B. Malik, and Tatyana Voyno-Yasenetskaya
Circ. Res. 2007;101:50-58; published online before print as doi:10.1161/CIRCRESAHA.106.145847 [Abstract] [Full text]

Molecular Medicine
Genetic Deletion of Pregnancy-Associated Plasma Protein-A Is Associated With Resistance to Atherosclerotic Lesion Development in Apolipoprotein E–Deficient Mice Challenged With a High-Fat Diet: Sean C. Harrington, Robert D. Simari, and Cheryl A. Conover
Circ. Res. 2007;100:1696-1702; published online before print as doi:10.1161/CIRCRESAHA.106.146183 [Abstract] [Full text]

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